The 49ers and Buccaneers have taken major injury hits. With Christian McCaffery scheduled to return from IR and Mike Evans and Chris Godwin gone, the Buccaneers are in worse shape than the 49ers.

The 49ers are 4-4 without the offensive player of the year. I’m 1-2 away from home.

The Buccaneers (4-5) started the season strong, but have lost four of their last five games and the last three they have played. The silver lining for the Bucs is Baker Mayfield’s play was phenomenal.

With both teams on the outside looking in to the playoffs, this week’s game has massive implications for each team.

Listen to the Bet the Edge podcast as hosts, Jay Croucher and Drew Dinsick, provide listeners with clear insight, market analysis and statistical data to help bettors gain more information before placing their bets. So whether you’re targeting spreads and totals, looking for value in the futures markets, or circling player props, listen to their podcast to give yourself that extra edge.

How to watch San Francisco 49ers @ Tampa Bay Buccaneers

· Date: Sunday, November 10, 2024
· Time: 1:00 PM ET
· Website: Raymond James Stadium
· City: Tampa, FL
· TV/Streaming: FOX

NBC Sports is your home for all the latest updates on this game, with live odds, player news, expert analysis and predictions.

Latest game odds for San Francisco 49ers @ Tampa Bay Buccaneers

The latest Friday odds, courtesy of DraftKings:

· Money line: San Francisco 49ers (-250), Tampa Bay Buccaneers (+210)
· Spread: 49ers -6.5
· Total: 50.5

The line opened at 49ers -6, but moved up to -6.5 with the new Christian McCaffery.

NBC Sports Bet Best Bets

NBC Sports analyst Brad Thomas (@MrBradThomas) looks at over 50.0:
“Sometimes in betting, there are things that are too good to be true, or too obvious, where they look harder. Initially I thought it was from the total. There have been at least 50 points in the Buccaneers’ last five games and the 49ers’ last two of three games.

It’s hard to bet on this pattern alone. It’s alluring though. Buccaneers are 29 years old^th in EPA/Play and 31^St in the defense success rate. While the Niners have generally been a strong defensive unit, this season they have struggled.

The Bucs have put up points against nearly every team they’ve played, and with McCaffery back in action, they Niners will score in bunches. Taking the lead in this game”

San Francisco 49ers @ Tampa Bay Buccaneers Team Stats, Betting Trends

· The 49ers have won four of their last five games against NFC South teams
· The Buccaneers have lost three straight after a 4-2 start
· Four of the Buccaneers’ last five home games have gone over the total

San Francisco 49ers @ Tampa Bay Buccaneers quarterback matchup

· 49ers: Brock Purdy has had his ups and downs this season. He has thrown seven interceptions and just 10 touchdowns this season.
· Buccaneers: Baker Mayfield has cemented himself as the Buccaneers’ starting quarterback for the foreseeable future. He threw for 23 touchdowns and 2,389 yards. He is first in touchdowns and second in passing yards.

Player news and injuries

49ers
· K Jake Moody (ankle) is questionable
· WR Jauan Jennings (hip) is questionable
· RB Jordan Mason (shoulder) is questionable
Buccaneers
· QB Baker Mayfield (Shoulder) is probable
· WR Mike Evans (Hamstring) is out
· RB Bucky Irving (toe) is questionable
· WR Sterling Shepard (hamstring) is questionable
· WR Jalen McMillan (hamstring) is questionable
· DT Vita Vea (hip) is questionable

Rotoworld still brings you the latest news and tools for the NFL, including game predictions, player props, futures and trends!

Follow our experts on social media to keep up with all the latest content from the staff:
· Vaughn Dalzell (@VmoneySports)
· Brad Thomas (@MrBradThomas)
· Jay Croucher (@croucherJD)
· Drew Dinsick (@whale_capper)