A three-vehicle crash shut down all lanes of northbound Highway 400 in Vaughan during Tuesday morning’s rush hour.

The collision happened at around 10.30pm on Monday, north of Teston Road.

A crossover vehicle struck an SUV, causing the SUV to rear-end a tractor trailer, according to Ontario Provincial Police.

The driver and a passenger in the SUV were taken to the hospital with life-threatening injuries, police said.

The extensive cleanup required means the northbound lanes are likely to remain closed until around 8am

The Aurora OPP Detachment is investigating the crash. Anyone with information or dash cam video is asked to contact police.