Alabama football aims for a win over Missouri, fresh off the Crimson Tide’s second loss of the season under new coach Kalen DeBoer.

No. 15 Alabama is in a playoff-like scenario. It can’t afford another loss if it wants to make the first 12-team College Football Playoff. The Crimson Tide have lost to No. 25 Vanderbilt and No. 7 Tennessee so far this season.

Now they’ll face a No. 21 Missouri team that’s lost just once this season: On the road to Texas A&M.

The matchup between the Crimson Tide and Tigers also marks the first homecoming game for DeBoer, who took over this season for Nick Saban.

Kickoff is set for 2:45 pm CT at Bryant-Denny Stadium. The match can be watched on ABC.

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Second trimester

— Missouri will continue on its way. Third-and-6 from the Alabama 48-yard line. Missouri cannot complete the pass. The Tigers will need to step up.

— 1:58 p.m.: Alabama takes over at its own 9-yard line after punt. Milroe completes a pass to Germie Bernard for 12 yards. Down first. The next play, Jam Miller runs for the first down. Back-to-back first downs for Alabama.

First trimester

— Missouri starts on offense. Jihaad Campbell gets a second down sack to set up third and 18. Then the third down pass is short on first down. So the Tigers pass three times to start.

— 12:53 Alabama takes over on their own 21-yard line. It looked like the Crimson Tide was about to go for an immediate third down, but a facemask after the play gives the Crimson Tide a 15-yard gain and another set of downs.

— Next first down, Cole Adams gets hurt and has to go to the injury tent. The next play, Kendrick Law runs for a 21-yard first down around the left end.

— Third-and-5 from the Missouri 25-yard line, Alabama runs a punt for a loss. The Crimson Tide will attempt a field goal. Graham Nicholson converts the 47-yard field goal attempt to give Alabama has a 3-0 lead over Missouri with 8:50 left in the first trimester.

— 8:50: Missouri kicks off at their own 25-yard line. Third and 5 on Missouri 30, pass falls incomplete. Second consecutive three-and-out.

— 7:29: Alabama will take over at their own 26-yard line. Third-and-9 at the Alabama 27-yard line: Kobe Prentice can’t complete the catch down the sideline. Tide must bridge.

— 6:45: Missouri kicks off at their own 19-yard line. On third-and-7, Missouri is called for delay of game. Alabama is called for a personal foul after the play. As a result, Missouri gets a first down. LT Overton sacked Brady Cook, but apparently Overton thought the play was on.

— Third-and-4 from Missouri 49, pass incomplete. The Tigers will punt.

— 2:31: Alabama takes over on their own 7-yard line. Alabama goes three and comes up with a sack on third down.

— :35: Missouri takes over at their own 48-yard line.

— End of first quarter: Alabama leads Missouri 3-0.

Alabama Football Injury Report

• Starting safety Keon Sabb sat out with a lower-body injury. He had been sent off earlier in the week. Backup linebacker Cayden Jones is also out.
• Meanwhile, defensive back Red Morgan is listed as a game-time decision, according to Saturday afternoon’s availability report released before kickoff.

Missouri Injury Report

• Starting quarterback Brady Cook is listed as a game-time decision on the injury report released 90 minutes before kickoff.
• Tigers starting running back Nate Noel is out. Missouri will also be without receiver Mookie Cooper, defensive end Darris Smith, quarterback Sam Horn, linebacker Khalil Jacobs and defensive end Joe Moore.